National AIDS Control Programme is being implemented through National AIDS Control Organization (NACO), New Delhi, under Ministry of Health & Family Welfare, Government of India with the support of DFID & World Bank fund. Accordingly autonomous organizations namely; State AIDS Control Societies have been formed in each of the States for smooth implementation of the programme.

From 1992 - 1999 = National AIDS Control Programme, Phase - I (NACP-I) was implemented by Government of Orissa under Director, Health Services.
From 1999 13.07.04: - Programme under NACP II was implemented through Orissa State Health & Family Welfare Society under the name of State AIDS Cell (SAC).
From 14.07.2004 05.07.06: - As per the direction of NACO, a new Society, i.e., Orissa State AIDS Control Society (OSACS) was formed and has been registered under Societies Registration Act XXI of 1860 vide Regd. No. 21886/64 of 2004-2005.